PROSPER is an integrated feature-based webserver for in silico prediction of protease substrates and their cleavage sites for twenty-four different protease types, covering four major protease families- Aspartic (A), Cysteine (C), Metallo (M) and Serine (S).

Important Notice: You have been redirected from http://lightning.med.monash.edu.au/PROSPER to this new PROSPER server. Kindly update your bookmarks to: https://prosper.erc.monash.edu.au

Please input the protein sequence of a substrate in the FASTA format below (example):

 

ID: (optional, your given name of the sequence)

Email address: (mandatory, where results will be sent to)

 

submit

 

Citation   

Important Notice: We rely on good outcomes from the use of the bioinformatics tools that we have developed for funding and other important considerations. To continue this high-quality service and to enable the further development of cutting-edge tools that meet users' needs, we ask you to consider citing the publication on PROSPER if you get great outcomes from using our service:
Song J, Tan H, Perry AJ, Akutsu T, Webb GI, Whisstock JC and Pike RN. PROSPER: an integrated feature-based tool for predicting protease substrate cleavage sites. PLoS ONE, 2012, 7(11): e50300.